Ciplar Plus 10 Tablet SR is a combination of two medicines (Propranolol 40mg + Flunarizine 10mg that helps prevent migraine headaches. However, it is not meant to be used for the treatment of acute migraine attacks. This medicine should be taken on an empty stomach, preferably at night, and at the same time regularly. The dose and duration of treatment will be determined by your doctor based on your condition and response to the medicine. It is important to take the medicine for the prescribed duration to get the maximum benefit.In addition to taking this medicine, certain lifestyle modifications like avoiding stress, smoking, and processed foods may help the medicine work better. However, it is important to consult your doctor before making any lifestyle changes.Like any medicine, Ciplar Plus 10 Tablet SR may cause some side effects. Some common side effects of this medicine include weight gain, slow heart rate, tiredness, depression, drowsiness, and cold extremities. This medicine may also cause sleepiness, so it is advisable not to drive or engage in activities that require mental focus or rise suddenly from a sitting position.Ciplar Plus 10 Tablet SR can also affect blood sugar and blood pressure levels. Therefore, it is important to monitor these levels regularly while taking the medicine. Inform your doctor if you have liver or kidney disease, depression, or if you are pregnant or breastfeeding. Also, inform your doctor about all other medicines you are taking as they may affect the effectiveness or the way the medicine works.