Sompraz HP Combipack is a combination medication that contains two antibiotics (clarithromycin and amoxicillin) and an antacid (esomeprazole). It is primarily used to treat peptic ulcer disease caused by the bacteria Helicobacter pylori (H. pylori). The antibiotics work by killing the bacteria, while the antacid helps to reduce stomach acid levels and relieve symptoms of acidity and discomfort related to the infection. To ensure optimal efficacy, it should be taken on an empty stomach at a fixed time, as prescribed by your doctor. It is important not to exceed the prescribed dose, and the full course of treatment must be completed even if symptoms improve. Missing a dose should be taken as soon as you remember, but the missed dose should not be doubled if it's almost time for the next dose. Nausea, vomiting, diarrhea, and rashes are common side effects of this medicine. If any of these side effects worsen, consult your doctor immediately. Allergic reactions such as rashes, itching, swelling, or shortness of breath may occur and require immediate medical attention. It is essential to inform your doctor of all the medicines you are taking for any health condition before taking this medicine. Pregnant or breastfeeding women should consult their doctor before taking it. It is advisable to avoid drinking alcohol while taking this medicine as it may cause excessive drowsiness. While this medicine usually does not impair your ability to drive, avoid driving if it makes you feel sleepy or dizzy.